TrkB agonist 7,8-dihydroxyflavone reverses an induced prepulse inhibition deficit selectively in maternal immune activation offspring: implications for schizophrenia
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DOI: 10.1097/fbp.0000000000000632
Abstract: Reduced brain-derived neurotrophic factor (BDNF) signalling has been implicated in schizophrenia endophenotypes, including deficits in prepulse inhibition (PPI). Maternal immune activation (MIA) is a widely used neurodevelopmental animal model for schizophrenia but it is unclear… read more here.
Keywords: bdnf; maternal immune; prepulse inhibition; trkb agonist ... See more keywords