BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the “weaver” mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor
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DOI: 10.1016/j.neuropharm.2017.04.043
Abstract: Neurotrophic factors are among the most promising treatments aiming at slowing or stopping and even reversing Parkinson's disease (PD). However, in most cases, they cannot readily cross the human blood-brain-barrier (BBB). Herein, we propose as… read more here.
Keywords: bnn; neurotrophin receptor; bnn synthetic; trkb neurotrophin ... See more keywords