Tissue-resident memory T (TRM ) cells: front-line workers of the immune system.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250060
Abstract: Tissue-resident memory T (TRM ) cells play a vital role in local immune protection against infection and cancer. The location of TRM cells within peripheral tissues at sites of pathogen invasion allows for the rapid… read more here.
Keywords: resident memory; tissue resident; memory trm; trm cells ... See more keywords
Pathogenic role of tissue-resident memory T cells in autoimmune diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2018.03.014
Abstract: The tissue-resident memory T (TRM) cells constitute a newly identified subset of memory T cells which are non-circulating and they persist for long-term in epithelial barrier tissues, including skin, lung, gastrointestinal tract and reproductive tract,… read more here.
Keywords: memory cells; autoimmune diseases; tissue resident; trm cells ... See more keywords
Heterogeneity of Tissue Resident Memory T cells.
Sign Up to like & getrecommendations! Published in 2022 at "Immunology letters"
DOI: 10.1016/j.imlet.2022.02.009
Abstract: Non-lymphoid organs, in mice and humans, contain CD8+ tissue-resident memory T (TRM) cells. They play important roles in tissue homeostasis as well as defence against infections and cancer. TRM cells have common characteristics that enables… read more here.
Keywords: trm cells; tissue; resident memory; tissue resident ... See more keywords
CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin
Sign Up to like & getrecommendations! Published in 2017 at "Immunity"
DOI: 10.1016/j.immuni.2017.01.009
Abstract: SUMMARY Tissue‐resident memory T (Trm) cells form a heterogeneous population that provides localized protection against pathogens. Here, we identify CD49a as a marker that differentiates CD8+ Trm cells on a compartmental and functional basis. In… read more here.
Keywords: cd8; skin; trm cells; expression ... See more keywords
Tissue-specific differentiation of CD8+ resident memory T cells.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in immunology"
DOI: 10.1016/j.it.2021.08.002
Abstract: CD8+ tissue-resident memory T (TRM) cells play crucial roles in defense against infections and cancer and have been implicated in autoimmune diseases such as psoriasis. In mice and humans, they exist in all nonlymphoid organs… read more here.
Keywords: tissue specific; cd8; trm cells; tissue ... See more keywords
Significance of IL-17A-producing CD8+CD103+ skin resident memory T cells in psoriasis lesion and their possible relationship to clinical course.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2019.06.002
Abstract: BACKGROUND A number of studies have shown the relationship between the pathogenesis of psoriasis and skin resident memory T (TRM) cells. OBJECTIVE To investigate the cytokine profile of TRM cells from skin lesions of psoriasis… read more here.
Keywords: psoriasis; cd103; trm cells; cd8 cd103 ... See more keywords
IL-22 in Peyer's patches
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni.3786
Abstract: Pneumonia is caused by pathobionts present in the respiratory tract, such as Streptococcus pneumoniae. In Mucosal Immunology, Mizgerd and colleagues show that resistance to pneumonia is provided by highly localized resident memory T cells (TRM… read more here.
Keywords: protection; peyer patches; immunology; trm cells ... See more keywords
Tissue-resident memory T cells at the center of immunity to solid tumors
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0114-2
Abstract: Immune responses in tissues are constrained by the physiological properties of the tissue involved. Tissue-resident memory T cells (TRM cells) are a recently discovered lineage of T cells specialized for life and function within tissues.… read more here.
Keywords: solid tumors; memory cells; tissue resident; trm cells ... See more keywords
Anticipatory immunity
Sign Up to like & getrecommendations! Published in 2019 at "Nature Immunology"
DOI: 10.1038/s41590-019-0483-1
Abstract: Tissue-resident memory T cells (TRM cells) serve important roles in maintaining immunological defence at tissue barriers and by and large keep to their given tissue environment. In Science Immunology, Gratz and colleagues use a combination… read more here.
Keywords: anticipatory immunity; tissue; immunology; trm cells ... See more keywords
Inhibiting phagocytosis
Sign Up to like & getrecommendations! Published in 2019 at "Nature Immunology"
DOI: 10.1038/s41590-019-0485-z
Abstract: Tissue-resident memory T cells (TRM cells) serve important roles in maintaining immunological defence at tissue barriers and by and large keep to their given tissue environment. In Science Immunology, Gratz and colleagues use a combination… read more here.
Keywords: skin; trm cells; tissue; inhibiting phagocytosis ... See more keywords
TRM cells hit the road
Sign Up to like & getrecommendations! Published in 2019 at "Nature Immunology"
DOI: 10.1038/s41590-019-0487-x
Abstract: Tissue-resident memory T cells (TRM cells) serve important roles in maintaining immunological defence at tissue barriers and by and large keep to their given tissue environment. In Science Immunology, Gratz and colleagues use a combination… read more here.
Keywords: hit road; cells hit; trm cells; tissue ... See more keywords