Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway
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DOI: 10.1371/journal.pgen.1007288
Abstract: Modification defects in the tRNA anticodon loop often impair yeast growth and cause human disease. In the budding yeast Saccharomyces cerevisiae and the phylogenetically distant fission yeast Schizosaccharomyces pombe, trm7Δ mutants grow poorly due to… read more here.
Keywords: gaac activation; trnaphe; anticodon loop; trm7 mutants ... See more keywords