TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice
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DOI: 10.1093/nar/gkae520
Abstract: Abstract In higher eukaryotes, tRNA methyltransferase 10A (TRMT10A) is responsible for N1-methylguanosine modification at position nine of various cytoplasmic tRNAs. Pathogenic mutations in TRMT10A cause intellectual disability, microcephaly, diabetes, and short stature in humans, and… read more here.
Keywords: codon translation; brain; trmt10a; initiator methionine ... See more keywords