Honeybee Iflaviruses Pack Specific tRNA Fragments from Host Cells in Their Virions
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DOI: 10.1002/cbic.202200281
Abstract: The Picornavirales include viruses that infect vertebrates, insects, and plants. It was believed that they pack only their genomic mRNA in the particles; thus, we envisaged these viruses as excellent model systems for studies of… read more here.
Keywords: specific trna; pack specific; trna fragments; iflaviruses pack ... See more keywords
tRNA fragments (tRFs) guide Ago to regulate gene expression post-transcriptionally in a Dicer-independent manner.
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DOI: 10.1261/rna.066126.118
Abstract: tRNA related RNA fragments (tRFs), also known as tRNA-derived RNAs (tdRNAs), are abundant small RNAs reported to be associated with Argonaute proteins, yet their function is unclear. We show that endogenous 18 nucleotide tRFs derived… read more here.
Keywords: post transcriptionally; dicer independent; trf; trna fragments ... See more keywords
Possible Roles of tRNA Fragments, as New Regulatory ncRNAs, in the Pathogenesis of Rheumatoid Arthritis
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DOI: 10.3390/ijms22179481
Abstract: Understanding the pathophysiology of rheumatoid arthritis (RA) has led to the successful development of molecule-targeted drugs for the treatment of RA. However, some RA patients are refractory to these treatments, suggesting that the pathological mechanism… read more here.
Keywords: possible roles; coding rna; trna fragments; rheumatoid arthritis ... See more keywords