Identification and Functional Characterization of Divergent 3’-Phosphate tRNA Ligase From Entamoeba histolytica
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.746261
Abstract: HSPC117/RtcB, 3’-phosphate tRNA ligase, is a critical enzyme involved in tRNA splicing and maturation. HSPC117/RtcB is also involved in mRNA splicing of some protein-coding genes including XBP-1. Entamoeba histolytica, a protozoan parasite responsible for human… read more here.
Keywords: phosphate trna; entamoeba histolytica; trna ligase; histolytica ... See more keywords
Molecular architecture of the human tRNA ligase complex
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.71656
Abstract: RtcB enzymes are RNA ligases that play essential roles in tRNA splicing, unfolded protein response, and RNA repair. In metazoa, RtcB functions as part of a five-subunit tRNA ligase complex (tRNA-LC) along with Ddx1, Cgi-99,… read more here.
Keywords: trna ligase; ligase complex; molecular architecture; human trna ... See more keywords