Conservation and Diversification of tRNA t6A-Modifying Enzymes across the Three Domains of Life
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DOI: 10.3390/ijms232113600
Abstract: The universal N6-threonylcarbamoyladenosine (t6A) modification occurs at position 37 of tRNAs that decipher codons starting with adenosine. Mechanistically, t6A stabilizes structural configurations of the anticodon stem loop, promotes anticodon–codon pairing and safeguards the translational fidelity.… read more here.
Keywords: trna t6a; life; conservation diversification; t6a ... See more keywords