Principles of tRNAAla Selection by Alanyl–tRNA Synthetase Based on the Critical G3·U70 Base Pair
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DOI: 10.1021/acsomega.9b01827
Abstract: Throughout evolution, the presence of a single G3·U70 mismatch in the acceptor stem of tRNAAla is the major determinant for aminoacylation with alanine by alanyl–tRNA synthetase (AlaRS). Recently reported crystal structures of the complexes AlaRS–tRNAAla/G3·U70… read more here.
Keywords: trna synthetase; alanyl trna; trnaala u70; base pair ... See more keywords