GCN2 kinase-mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln (CUG) charging under amino acid starvation.
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DOI: 10.1002/1873-3468.14628
Abstract: Each tRNA is aminoacylated (charged) with a genetic codon-specific amino acid. It remains unclear what factors are associated with tRNA charging and how tRNA charging is maintained. By using the individual tRNA acylation PCR (i-tRAP)… read more here.
Keywords: glutamine level; acid starvation; cug; amino acid ... See more keywords