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   Articles with "trnaphe" as a keyword



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Structural Stability of the Anticodon Stem Loop Domains of the Unmodified Yeast and Escherichia coli tRNAPhe: Differing Views from Different Force Fields

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recommendations! Published in 2019 at "ACS Omega"

DOI: 10.1021/acsomega.8b02383

Abstract: Unmodified tRNAs provide essential insights into the structural and functional role of the extensive and diverse post-transcriptional modifications that naturally occur in tRNAs. The X-ray crystal structure of the completely unmodified Escherichia coli tRNAPhe showed… read more here.

Keywords: coli trnaphe; anticodon stem; stem loop; escherichia coli ... See more keywords

A novel assay provides insight into tRNAPhe retrograde nuclear import and re-export in S. cerevisiae

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recommendations! Published in 2020 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaa879

Abstract: Abstract In eukaryotes, tRNAs are transcribed in the nucleus and subsequently exported to the cytoplasm where they serve as essential adaptor molecules in translation. However, tRNAs can be returned to the nucleus by the evolutionarily… read more here.

Keywords: export; trnaphe; import; retrograde nuclear ... See more keywords
Photo by apchf from unsplash

Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway

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recommendations! Published in 2018 at "PLoS Genetics"

DOI: 10.1371/journal.pgen.1007288

Abstract: Modification defects in the tRNA anticodon loop often impair yeast growth and cause human disease. In the budding yeast Saccharomyces cerevisiae and the phylogenetically distant fission yeast Schizosaccharomyces pombe, trm7Δ mutants grow poorly due to… read more here.

Keywords: gaac activation; trnaphe; anticodon loop; trm7 mutants ... See more keywords

The Mitochondrial tRNAPhe 625G>A Mutation in Three Han Chinese Families With Cholecystolithiasis

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recommendations! Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.814729

Abstract: In this study, we assessed three Chinese families with inherited cholecystolithiasis and conducted the clinical, genetic, and molecular characterization of these subjects. Eight of eighteen matrilineal relatives had a clinical phenotype in these three families.… read more here.

Keywords: cholecystolithiasis; 625g mutation; trnaphe 625; chinese families ... See more keywords