PD-L1/L2 protein levels rapidly increase on monocytes via trogocytosis from tumor cells in classical Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0737-9
Abstract: In classical Hodgkin lymphoma (cHL)—characterized by the presence of Hodgkin and Reed-Sternberg (HRS) cells—tumor-associated macrophages (TAMs) play a pivotal role in tumor formation. However, the significance of direct contact between HRS cells and TAMs has… read more here.
Keywords: trogocytosis; classical hodgkin; hrs; hrs cells ... See more keywords
Vaginal neutrophils eliminate sperm by trogocytosis.
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DOI: 10.1093/humrep/deaa198
Abstract: STUDY QUESTION What is the vaginal polymorphonuclear (PMN) spermicidal mechanism to reduce the excess of sperm? SUMMARY ANSWER We show that PMNs are very efficient at killing sperm by a trogocytosis-dependent spermicidal activity independent of… read more here.
Keywords: trogocytosis; study; pmns; sperm trogocytosis ... See more keywords
Marginal zone B cells acquire dendritic cell functions by trogocytosis
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DOI: 10.1126/science.abf7470
Abstract: Marginal zone (MZ) B cells produce broad-spectrum antibodies that protect against infection early in life. In some instances, antibody production requires MZ B cells to display pathogen antigens bound to major histocompatibility complex class II… read more here.
Keywords: mhc; trogocytosis; cdcs; zone cells ... See more keywords
Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum
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DOI: 10.1128/mbio.00068-19
Abstract: Entamoeba histolytica causes amoebiasis, a potentially fatal diarrheal disease. Abscesses in organs such as the liver can occur when amoebae are able to breach the intestinal wall and travel through the bloodstream to other areas… read more here.
Keywords: trogocytosis; histolytica; cell; cell membrane ... See more keywords
Entamoeba histolytica Develops Resistance to Complement Deposition and Lysis after Acquisition of Human Complement-Regulatory Proteins through Trogocytosis
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DOI: 10.1128/mbio.03163-21
Abstract: Entamoeba histolytica is the cause of amoebiasis, a diarrheal disease of global importance. While infection is often asymptomatic, the trophozoite (amoeba) form of this parasite is capable of invading and ulcerating the intestine and can… read more here.
Keywords: lysis; trogocytosis; deposition; complement ... See more keywords
CAR T Cell-Driven Trogocytosis Induces Antigen-Low Leukemia Relapse.
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DOI: 10.1158/2159-8290.cd-rw2019-053
Abstract: CAR T cells reduce target antigen density on tumor cells and T cell activity via trogocytosis. read more here.
Keywords: driven trogocytosis; trogocytosis; cell driven; trogocytosis induces ... See more keywords
Hijacking TYRO3 from Tumor Cells via Trogocytosis Enhances NK-cell Effector Functions and Proliferation
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DOI: 10.1158/2326-6066.cir-20-1014
Abstract: The authors show TYRO3 is transferred to natural killer (NK) cells via trogocytosis from feeder cells, improving NK-cell proliferation ex vivo. This provides a potential novel strategy to manufacture NK cells for adoptive-cell transfer cancer… read more here.
Keywords: cells via; trogocytosis; proliferation; cell ... See more keywords
Gnawing Between Cells and Cells in the Immune System: Friend or Foe? A Review of Trogocytosis
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DOI: 10.3389/fimmu.2022.791006
Abstract: Trogocytosis occurs when one cell contacts and quickly nibbles another cell and is characterized by contact between living cells and rapid transfer of membrane fragments with functional integrity. Many immune cells are involved in this… read more here.
Keywords: gnawing cells; trogocytosis; friend foe; cells cells ... See more keywords