Embryo‐fetal developmental toxicity and toxicokinetics of loxoprofen tromethamine intravenously administered to pregnant rats
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DOI: 10.1002/bdr2.2116
Abstract: Loxoprofen tromethamine is a novel structural compound related to loxoprofen. It has been used for the treatment of pain and inflammation. However, the embryo‐fetal developmental toxicity (EFDT) of loxoprofen tromethamine has not been evaluated in… read more here.
Keywords: developmental toxicity; fetal developmental; embryo fetal; toxicokinetics loxoprofen ... See more keywords
Pharmacokinetic and Pharmacodynamic Characteristics of Pelubiprofen Tromethamine vs. Pelubiprofen in Healthy Subjects
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DOI: 10.3390/pharmaceutics15041280
Abstract: Compared to pelubiprofen, a cyclooxygenase-2-selective inhibitor, pelubiprofen tromethamine has been reported to exhibit improved solubility and absorption. Pelubiprofen tromethamine combines the anti-inflammatory effect of pelubiprofen with the gastric protective function of tromethamine salt, making it… read more here.
Keywords: pharmacokinetic pharmacodynamic; pelubiprofen tromethamine; tromethamine; study ... See more keywords