Trop2 Forms a Stable Dimer with Significant Structural Differences within the Membrane-Distal Region as Compared to EpCAM
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DOI: 10.3390/ijms221910640
Abstract: Trop2 is a cell-surface transmembrane glycoprotein involved in the maintenance of epithelial tissue integrity and is an important carcinoma marker. It shares similar claudin-interaction capacity with its paralogue EpCAM, and both are implicated in signaling… read more here.
Keywords: trop2; dimer; forms stable; trop2 forms ... See more keywords