Influence of nano‐zinc oxide on tropane alkaloid production, h6h gene transcription and antioxidant enzyme activity in Hyoscyamus reticulatus L. hairy roots
Sign Up to like & getrecommendations! Published in 2019 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201800087
Abstract: The use of nanotechnology and biotechnology to improve the production of plant bioactive compounds is growing. Hyoscyamus reticulatus L. is a major source of tropane alkaloids with a wide therapeutic use, including treatment of Parkinson's… read more here.
Keywords: h6h gene; hairy roots; zno; tropane ... See more keywords
Discovery and Engineering of the Cocaine Biosynthetic Pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c09091
Abstract: Cocaine, the archetypal tropane alkaloid from the plant genus Erythroxylum, has recently been used clinically as a topical anesthesia of the mucous membranes. Despite this, the key biosynthetic step of the requisite tropane skeleton (methylecgonone)… read more here.
Keywords: engineering cocaine; pathway; tropane; cocaine ... See more keywords
Genomic and structural basis for evolution of tropane alkaloid biosynthesis.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2302448120
Abstract: The tropane alkaloids (TAs) cocaine and hyoscyamine have been used medicinally for thousands of years. To understand the evolutionary origins and trajectories of serial biosynthetic enzymes of TAs and especially the characteristic tropane skeletons, we… read more here.
Keywords: biosynthesis; genomic structural; structural basis; analysis ... See more keywords
An overview of tropane alkaloids from Datura stramonium L.
Sign Up to like & getrecommendations! Published in 2020 at "Phytopathology"
DOI: 10.22271/phyto
Abstract: Datura stramonium L., a wild-growing plant of the Solanaceae family, is widely distributed throughout the world. It contains a variety of tropane alkaloids such as atropine, hyoscyamine, and scopolamine In Ayurvedic medicine, D. stramonium has… read more here.
Keywords: tropane alkaloids; tropane; overview tropane; datura stramonium ... See more keywords