VEGF is an essential retrograde trophic factor for motoneurons
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2202912119
Abstract: Significance Vascular endothelial growth factor (VEGF) plays a critical role in motoneurons. Low levels of VEGF lead to motoneuron degeneration in mutant mice, which can be alleviated by VEGF delivery. We have recently shown that… read more here.
Keywords: essential retrograde; retrograde; vegf essential; factor ... See more keywords
Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types
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DOI: 10.1523/eneuro.0511-22.2023
Abstract: Abstract Vagal sensory neurons (VSNs) located in the nodose ganglion provide information, such as stomach stretch or the presence of ingested nutrients, to the caudal medulla via specialized cell types expressing unique marker genes. Here,… read more here.
Keywords: cell; cell types; factor; factor sensitivity ... See more keywords
Antidepressant-like effects of trophic factor receptor signaling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.958797
Abstract: A significant body of research has demonstrated that antidepressants regulate neurotrophic factors and that neurotrophins themselves are capable of independently producing antidepressant-like effects. While brain derived neurotrophic factor (BDNF) remains the best studied molecule in… read more here.
Keywords: effects trophic; like effects; antidepressant like; factor ... See more keywords