Down-regulation of CCR7 via AKT pathway and GATA2 inactivation suppressed trophoblast migration and invasion in recurrent spontaneous abortion
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz172
Abstract: Abstract The underlying mechanism of the chemokine-C receptor 7 (CCR7) that leads to aberrant trophoblast migration and invasion in recurrent spontaneous abortion (RSA) remains unknown. CCR7 is considered crucial for migration and invasion and has… read more here.
Keywords: trophoblast migration; migration invasion; ccr7; gata2 ... See more keywords
TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia
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DOI: 10.3389/fcell.2022.810633
Abstract: Preeclampsia (PE) is a serious disease during pregnancy that affects approximately eight million mothers and infants worldwide each year and is closely related to abnormal trophoblast function. However, research on placental trophoblast functional abnormalities is… read more here.
Keywords: trophoblast migration; migration invasion; tagln2 regulated; tagln2 ... See more keywords
Constitutive Signaling by the Human Cytomegalovirus G Protein Coupled Receptor Homologs US28 and UL33 Enables Trophoblast Migration In Vitro
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DOI: 10.3390/v14020391
Abstract: Human cytomegalovirus (HCMV) encodes four homologs of G protein coupled receptors (vGPCRs), of which two, designated UL33 and US28, signal constitutively. UL33 and US28 are also conserved with chemokine receptors: US28 binds numerous chemokine classes,… read more here.
Keywords: ul33 us28; human cytomegalovirus; constitutive signaling; protein coupled ... See more keywords