Trophoblast survival signaling during human placentation requires HSP70 activation of MMP2-mediated HBEGF shedding
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DOI: 10.1038/cdd.2017.104
Abstract: Survival of trophoblast cells in the low oxygen environment of human placentation requires metalloproteinase-mediated shedding of HBEGF and downstream signaling. A matrix metalloproteinase (MMP) antibody array and quantitative RT-PCR revealed upregulation of MMP2 post-transcriptionally in… read more here.
Keywords: mmp2; hbegf shedding; human placentation; trophoblast survival ... See more keywords