15years of progress in gestational trophoblastic disease: Scoring, standardization, and salvage.
Sign Up to like & getrecommendations! Published in 2017 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2016.08.330
Abstract: Significant improvements in treatment and the understanding of gestational trophoblastic neoplasia have occurred in the last 15years. These diseases are almost always curable, and refractory patients have more options for salvage therapy. Recent improvements in… read more here.
Keywords: 15years progress; progress gestational; scoring standardization; gestational trophoblastic ... See more keywords
Heterozygous/dispermic complete mole confers a significantly higher risk for post-molar gestational trophoblastic disease
Sign Up to like & getrecommendations! Published in 2020 at "Modern Pathology"
DOI: 10.1038/s41379-020-0566-4
Abstract: Hydatidiform moles are classified at the genetic level as androgenetic complete mole and diandric-monogynic partial mole. Conflicting data exist whether heterozygous complete moles are more aggressive clinically than homozygous complete moles. We investigated clinical outcome… read more here.
Keywords: molar gestational; gestational trophoblastic; trophoblastic disease; post molar ... See more keywords
Gestational trophoblastic disease- rare, sometimes dramatic, and what we know so far.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2022.03.002
Abstract: Gestational trophoblastic disease (GTD) is a heterogeneous group of lesions that are characterized by the abnormal proliferation of the trophoblast. Morphology, behavior and clinical significance vary tremendously and range from benign, non-neoplastic lesions that cause… read more here.
Keywords: trophoblastic disease; gestational trophoblastic; disease rare; rare sometimes ... See more keywords
Gestational and Non-gestational Trophoblastic Neoplasia. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 032/049, April 2022)
Sign Up to like & getrecommendations! Published in 2022 at "Geburtshilfe und Frauenheilkunde"
DOI: 10.1055/a-1904-6461
Abstract: Abstract Purpose The aim was to develop and update a guideline which would improve the quality of care offered to women with gestational and non-gestational trophoblastic disease, a group of diseases characterized by their rarity… read more here.
Keywords: non gestational; trophoblastic disease; guideline; gestational trophoblastic ... See more keywords
Persistent trophoblastic disease at caesarean scar and its successful treatment with multiple dose systemic methotrexate after suction curettage
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2016.1244816
Abstract: Caesarean scar pregnancy (CSP) is defined as an ectopic pregnancy that implants in the myometrium at the site of an earlier caesarean section scar. It is one of the rarest forms of ectopic pregnanc... read more here.
Keywords: disease caesarean; persistent trophoblastic; scar successful; caesarean scar ... See more keywords
Can Ki67 and Caspase Predict Molar Progression?
Sign Up to like & getrecommendations! Published in 2019 at "Fetal and Pediatric Pathology"
DOI: 10.1080/15513815.2019.1608607
Abstract: Abstract Background: A clinical risk score has been introduced into the management of persistent trophoblastic disease to allow individualized therapy. However, this risk scoring system lacks histopathologic predictors. The hypothesis is that there are prognostic… read more here.
Keywords: persistent trophoblastic; trophoblastic disease; caspase; ki67 caspase ... See more keywords
PD‐L1 in gestational trophoblastic disease: an antibody evaluation
Sign Up to like & getrecommendations! Published in 2022 at "Acta Obstetricia et Gynecologica Scandinavica"
DOI: 10.1111/aogs.14404
Abstract: Treatment with antibodies directed against programed‐cell death ligand 1 (PD‐L1) is a novel therapy for patients with gestational trophoblastic disease. Assessment of PD‐L1 expression in tumor tissue is commonly used to identify patients who might… read more here.
Keywords: trophoblastic disease; gestational trophoblastic; antibody evaluation; disease antibody ... See more keywords
Management of a complete hydatidiform mole with a coexisting live fetus followed by successful treatment of maternal metastatic gestational trophoblastic disease: learning points
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-235028
Abstract: A 34-year-old patient had her first trimester Down syndrome scan followed by serial ultrasound scans which showed a single intrauterine pregnancy with multiple cystic areas in the anterior placenta. She presented in preterm labour with… read more here.
Keywords: gestational trophoblastic; complete hydatidiform; mole; trophoblastic disease ... See more keywords
Placental site trophoblastic tumour: the rarest subtype of gestational trophoblastic disease
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-235756
Abstract: Placental site trophoblastic tumour (PSTT) is a very rare form of gestational trophoblastic disease that grows slowly, secretes low levels of beta-subunit of human chorionic gonadotropin (β-hCG), presents late-onset metastatic potential and is resistant to… read more here.
Keywords: site trophoblastic; placental site; trophoblastic tumour; gestational trophoblastic ... See more keywords
Outcomes in the management of high-risk gestational trophoblastic neoplasia in trophoblastic disease centers in South America
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2020-001237
Abstract: Background South America has a higher incidence of gestational trophoblastic disease than North America or Europe, but whether this impacts chemotherapy outcomes is unclear. The purpose of this study was to evaluate outcomes among women… read more here.
Keywords: disease centers; risk; risk gtn; high risk ... See more keywords
Understanding and management of gestational trophoblastic disease
Sign Up to like & getrecommendations! Published in 2019 at "F1000Research"
DOI: 10.12688/f1000research.14953.1
Abstract: Gestational trophoblastic disease or neoplasia covers a spectrum of benign and malignant conditions arising from pregnancies with highly abnormal development of trophoblastic tissue. In this brief review, we discuss the different features of these different… read more here.
Keywords: management gestational; trophoblastic disease; gestational trophoblastic; understanding management ... See more keywords