Versican silencing in BeWo cells and its implication in gestational trophoblastic diseases
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DOI: 10.1007/s00418-018-1739-9
Abstract: Versican is a proteoglycan known to interact with cells to influence their ability to proliferate, differentiate, migrate, invade and assemble extracellular matrix, with all of these cell functions present during placentation. In the placenta, cytotrophoblast… read more here.
Keywords: trophoblastic diseases; silencing bewo; bewo cells; gestational trophoblastic ... See more keywords
Angiogenin and MMP-2 as potential biomarkers in the differential diagnosis of gestational trophoblastic diseases
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DOI: 10.1097/md.0000000000028768
Abstract: Abstract Background: Gestational trophoblastic diseases (GTDs) are characterized by vascular abnormalities of the trophoblast, but their pathogenesis is unknown. Angiogenin (ANG) and matrix metalloproteinase (MMP)-2, which are molecules implicated in the angiogenic process, may play… read more here.
Keywords: potential biomarkers; gestational trophoblastic; biomarkers differential; trophoblastic diseases ... See more keywords
PD-L1 Expression in Human Placentas and Gestational Trophoblastic Diseases
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DOI: 10.1097/pgp.0000000000000305
Abstract: One of the major immune checkpoints responsible for immune evasion in cancer cells is the interaction between programmed cell death-1 (PD-1) and its ligand (PD-L1). As human trophoblastic cells display many of the features of… read more here.
Keywords: trophoblastic diseases; trophoblastic cells; expression human; trophoblastic tumors ... See more keywords
Importance of pathological review of gestational trophoblastic diseases: results of the Belgian Gestational Trophoblastic Diseases Registry
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DOI: 10.1136/ijgc-2021-003312
Abstract: Objective To evaluate the added value of a centralized pathology review of the diagnoses of gestational trophoblastic diseases by expert pathologists and its potential impact on clinical management in a prospective multicenter study based on… read more here.
Keywords: expert pathologists; review; gestational trophoblastic; trophoblastic diseases ... See more keywords