PREDICT‐GTN 1: Can we improve the FIGO scoring system in gestational trophoblastic neoplasia?
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34352
Abstract: Gestational trophoblastic neoplasia (GTN) patients are treated according to the eight‐variable International Federation of Gynaecology and Obstetrics (FIGO) scoring system, that aims to predict first‐line single‐agent chemotherapy resistance. FIGO is imperfect with one‐third of low‐risk… read more here.
Keywords: figo scoring; trophoblastic neoplasia; scoring system; gestational trophoblastic ... See more keywords
Distinct microRNA profiles for complete hydatidiform moles at risk for malignant progression.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of obstetrics and gynecology"
DOI: 10.1016/j.ajog.2020.09.048
Abstract: BACKGROUND MicroRNAs (miRNAs) are small non-coding RNAs with important regulatory functions. While well-studied in cancer, less is known about the role of miRNAs in premalignant disease. Complete hydatidiform moles are benign forms of gestational trophoblastic… read more here.
Keywords: ontology; expression; gestational trophoblastic; complete moles ... See more keywords
Salvage chemotherapy for gestational trophoblastic neoplasia: Utility or futility?
Sign Up to like & getrecommendations! Published in 2017 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2017.04.017
Abstract: OBJECTIVE To determine the efficacy of chemotherapy after failed initial treatment in patients with high risk gestational trophoblastic neoplasia (GTN). METHODS We performed a retrospective IRB-approved chart review of all patients with GTN seen at… read more here.
Keywords: pfs; salvage chemotherapy; salvage; gestational trophoblastic ... See more keywords
The optimal management of brain metastases from gestational trophoblastic neoplasia
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2022.2038566
Abstract: ABSTRACT Introduction Gestational trophoblastic diseases and neoplasias (GTDs and GTNs) comprise a spectrum of diseases arising from abnormally proliferating placental/trophoblastic tissue following an antecedent molar or non-molar pregnancy. These can spread to the brain hematogenously… read more here.
Keywords: brain metastases; trophoblastic neoplasia; optimal management; gestational trophoblastic ... See more keywords
Can the FIGO 2000 scoring system for gestational trophoblastic neoplasia be simplified? A new retrospective analysis from a nationwide dataset
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DOI: 10.1093/annonc/mdx211
Abstract: Background Worldwide introduction of the International Fedaration of Gynaecology and Obstetrics (FIGO) 2000 scoring system has provided an effective means to stratify patients with gestational trophoblastic neoplasia to single- or multi-agent chemotherapy. However, the system… read more here.
Keywords: system; scoring system; figo 2000; gestational trophoblastic ... See more keywords
ABO blood type compatibility is not a risk factor for gestational trophoblastic neoplasia development from androgenetic complete hydatidiform moles
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13237
Abstract: Complete hydatidiform moles (CHMs) are allografts to patients in terms of an androgenetic origin. Thus, some immunological reactions may be involved in the development of gestational trophoblastic neoplasia (GTN) from CHMs. This study aimed to… read more here.
Keywords: abo blood; gestational trophoblastic; complete hydatidiform; hydatidiform moles ... See more keywords
GestaTIonal TrophoblAstic NeoplasIa Ultrasound assessMent: TITANIUM study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-000434
Abstract: Background There are limited data on ultrasound morphologic features of gestational trophoblastic neoplasia. A predictive model to determine predictors of response to therapy would be ideal in the management of patients with this rare disease.… read more here.
Keywords: single drug; risk; study; gestational trophoblastic ... See more keywords
EP1142 Gestational trophoblastic neoplasia: clinical presentation, treatment and outcomes
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2019-esgo.1183
Abstract: Introduction/Background To assess clinical and pathologic features of patients with gestational trophoblastic neoplasia (GTN), treatment and oncologic outcomes. Methodology Patients with GTN who had clinical data in our institution were identified. Data collected were age… read more here.
Keywords: risk; pregnancy; treatment; gestational trophoblastic ... See more keywords
Centralized surveillance of hydatidiform mole: 7-year experience from a regional hospital in China
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-002797
Abstract: Objective To assess the strategy and value of centralized surveillance of hydatidiform mole at a regional hospital in China and to investigate the necessity of prophylactic chemotherapy for high-risk complete hydatidiform mole. Methods Between February… read more here.
Keywords: risk; trophoblastic neoplasia; surveillance; hydatidiform ... See more keywords
The pregnancy that wasn’t: challenges of gestational trophoblastic neoplasia management in low- and middle-income countries
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DOI: 10.1136/ijgc-2022-003569
Abstract: CASE PRESENTATION A 26yearold G2 P0 A2 (gravida 2, parity 0, abortions 2) was referred to the gynecologic oncology clinic in Eldoret, Kenya with persistent vaginal bleeding 2 months after uterine evacuation for an 8… read more here.
Keywords: management low; trophoblastic neoplasia; neoplasia management; pregnancy challenges ... See more keywords
Gestational Trophoblastic Neoplasia with Gum Metastasis: A Case Study and Literature Review
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DOI: 10.1159/000506329
Abstract: Gestational trophoblastic neoplasia (GTN) is an uncommon group of pregnancy-related malignancies. Delayed diagnosis is a prognostic factor for worse outcome. GTN is even harder to diagnose if the site of metastasis is uncommon. The reported… read more here.
Keywords: case; gum; gestational trophoblastic; trophoblastic neoplasia ... See more keywords