Net charge and position 22 of the V3 loop are associated with HIV-1 tropism in recently infected female sex workers in Nairobi, Kenya
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DOI: 10.1097/md.0000000000032024
Abstract: Human immunodeficiency virus (HIV) infection affects around 37 million people worldwide, and in Kenya, key populations especially female sex workers (FSW), are thought to play a substantial role in the wider, mostly heterosexual HIV-1 transmission… read more here.
Keywords: tropic; hiv tropism; sex; tropism ... See more keywords
Emergence of a novel urogenital-tropic Neisseria meningitidis
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DOI: 10.1097/qco.0000000000000697
Abstract: Purpose of review Neisseria meningitidis (Nm) is primarily associated with asymptomatic nasopharyngeal carriage and invasive meningococcal disease (sepsis and meningitis), but like N. gonorrhoea (Ng), Nm can colonize urogenital and rectal mucosal surfaces and cause… read more here.
Keywords: novel urogenital; emergence novel; tropic; urogenital tropic ... See more keywords
Characterization of Macrophage-Tropic HIV-1 Infection of Central Nervous System Cells and the Influence of Inflammation
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DOI: 10.1128/jvi.00957-22
Abstract: The major feature of HIV-1 pathogenesis is the induction of an immunodeficient state in the face of an enhanced state of inflammation. However, for many of those infected, there can be an impact on the… read more here.
Keywords: tropic; cell; state; hiv ... See more keywords
Unique profile of predominant CCR5-tropic in CRF07_BC HIV-1 infections and discovery of an unusual CXCR4-tropic strain
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DOI: 10.3389/fimmu.2022.911806
Abstract: CRF07_BC is one of the most prevalent HIV-1 strains in China, which contributes over one-third of the virus transmissions in the country. In general, CRF07_BC is associated with slower disease progression, while the underlying mechanisms… read more here.
Keywords: tropic; hiv; crf07; cxcr4 tropic ... See more keywords
Different Patterns of HIV-1 Replication in MACROPHAGES is Led by Co-Receptor Usage
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DOI: 10.3390/medicina55060297
Abstract: Background and objectives: To enter the target cell, HIV-1 binds not only CD4 but also a co-receptor β-chemokine receptor 5 (CCR5) or α chemokine receptor 4 (CXCR4). Limited information is available on the impact of… read more here.
Keywords: mdm; cxcr4 tropic; receptor; replication ... See more keywords