Association of facet tropism and orientation with lumbar disc herniation in young patients
Sign Up to like & getrecommendations! Published in 2018 at "Neurological Sciences"
DOI: 10.1007/s10072-018-3270-0
Abstract: Facet tropism and orientation are thought to be associated with lumbar disc herniation (LDH), but the relationship is not well established. Moreover, the effect of facet joint on LDH has not been outlined in young… read more here.
Keywords: young patients; tropism orientation; facet joint; tropism ... See more keywords
Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Nature Nanotechnology"
DOI: 10.1038/s41565-021-00997-y
Abstract: This study shows that the supramolecular arrangement of proteins in nanoparticle structures predicts nanoparticle accumulation in neutrophils in acute lung inflammation (ALI). We observed homing to inflamed lungs for a variety of nanoparticles with agglutinated… read more here.
Keywords: arrangement; nanoparticle structures; inflammation; tropism ... See more keywords
Phenotypic co-receptor tropism and Maraviroc sensitivity in HIV-1 subtype C from East Africa
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20814-2
Abstract: Genotypic tropism testing (GTT) for co-receptor usage is a recommended tool for clinical practice before administration of the CCR5-antagonist maraviroc. For some isolates, phenotypic tropism testing (PTT) revealed discordant results with GTT. In this study,… read more here.
Keywords: tropic strains; hiv; hiv 1cea; east africa ... See more keywords
Performance comparison of next-generation sequencing platforms for determining HIV-1 coreceptor use
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42215
Abstract: The coreceptor used by HIV-1 must be determined before a CCR5 antagonist, part of the arsenal of antiretroviral drugs, is prescribed because viruses that enter cells using the CXCR4 coreceptor are responsible for treatment failure.… read more here.
Keywords: hiv; coreceptor; next generation; generation sequencing ... See more keywords
Deciphering foot-and-mouth disease (FMD) virus–host tropism
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2019.1567386
Abstract: Abstract The pattern of interactions between foot and mouth disease (FMD) viral protein 1 (VP1) with susceptible and resistant host integrins were deciphered. The putative effect of site-directed mutation on alteration of interaction is illustrated… read more here.
Keywords: foot mouth; vp1; fmd; host ... See more keywords
Net charge and position 22 of the V3 loop are associated with HIV-1 tropism in recently infected female sex workers in Nairobi, Kenya
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032024
Abstract: Human immunodeficiency virus (HIV) infection affects around 37 million people worldwide, and in Kenya, key populations especially female sex workers (FSW), are thought to play a substantial role in the wider, mostly heterosexual HIV-1 transmission… read more here.
Keywords: tropic; hiv tropism; sex; tropism ... See more keywords
Long-term antiretroviral therapy mitigates mortality and morbidity independent of HIV tropism: 18 years follow-up in a women's cohort
Sign Up to like & getrecommendations! Published in 2022 at "AIDS"
DOI: 10.1097/qad.0000000000003337
Abstract: Objective: CXCR4 (X4)-tropic HIV-1 was found previously to herald CD4+ cell depletion and disease progression in individuals who were antiretroviral-naive or took combination antiretroviral therapy (cART) for less than 5 years. We updated this finding by… read more here.
Keywords: long term; hiv tropism; antiretroviral therapy; tropism ... See more keywords
The relationship between facet tropism and cervical disc herniation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Anatomy"
DOI: 10.1111/joa.13151
Abstract: Many studies have demonstrated the association between facet tropism and disc herniation in the lumbar spine. Some of them found that lumbar disc herniation was on the side of the more sagittal facet joint interface.… read more here.
Keywords: group; disc herniation; tropism; facet tropism ... See more keywords
Mapping of host-parasite-microbiome interactions reveals metabolic determinants of tropism and tolerance in Chagas disease
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aaz2015
Abstract: Chemical cartography of experimental gastrointestinal Chagas disease identifies previously-unknown mechanisms of disease tolerance. Chagas disease (CD) is a parasitic disease caused by Trypanosoma cruzi protozoa, presenting with cardiomyopathy, megaesophagus, and/or megacolon. To determine the mechanisms… read more here.
Keywords: tolerance; infection; chagas disease; disease ... See more keywords
Molecular Mechanism of the Flexible Glycan Receptor Recognition by Mumps Virus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Virology"
DOI: 10.1128/jvi.00344-19
Abstract: Mumps virus (MuV) infection is characterized by parotid gland swelling and can cause pancreatitis, orchitis, meningitis, and encephalitis. MuV-related hearing loss is also a serious complication because it is usually irreversible. MuV outbreaks have been… read more here.
Keywords: gm2; tropism; muv; receptor ... See more keywords
Pace of Coreceptor Tropism Switch in HIV-1-Infected Individuals after Recent Infection
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.00793-17
Abstract: ABSTRACT HIV-1 entry into target cells influences several aspects of HIV-1 pathogenesis, including viral tropism, HIV-1 transmission and disease progression, and response to entry inhibitors. The evolution from CCR5- to CXCR4-using strains in a given… read more here.
Keywords: tropism switch; coreceptor; hiv infected; cxcr4 using ... See more keywords