cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Research"
DOI: 10.1186/s12931-018-0903-z
Abstract: BackgroundThe nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) signaling pathway, plays a critical role in the pathogenesis of pulmonary arterial hypertension (PAH); however, its exact molecular mechanism remains undefined.MethodsBiotin-cGMP pull-down assay was performed to search… read more here.
Keywords: tropomyosin myosin; tropomyosin; cgmp; actin tropomyosin ... See more keywords