Protein Scaffold‐Mediated Multi‐Enzyme Self‐Assembly and Ordered Co‐Immobilization of Flavin‐Dependent Halogenase‐Coenzyme Cycle System for Efficient Biosynthesis of 6‐Cl‐L‐Trp
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28871
Abstract: Flavin‐dependent halogenase (FDH) is highly prized in pharmaceutical and chemical industries for its exceptional capacity to produce halogenated aromatic compounds with precise regioselectivity. This study has devised a multi‐enzyme self‐assembly strategy to construct an effective… read more here.
Keywords: system; coenzyme; enzyme; enzyme self ... See more keywords
Breakpoint junction analysis for complex genomic rearrangements with the caldera volcano‐like pattern
Sign Up to like & getrecommendations! Published in 2020 at "Human Mutation"
DOI: 10.1002/humu.24108
Abstract: Chromosomal triplications can be classified into recurrent and nonrecurrent triplications. Most of the nonrecurrent triplications are embedded in duplicated segments, and duplication‐inverted triplication–duplication (DUP–TRP/INV‐DUP) has been established as one of the mechanisms of triplication. This… read more here.
Keywords: dup; breakpoint; analysis; trp ... See more keywords
TRP Channel Classification.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1088-4_1
Abstract: The transient receptor potential (TRP) ion channels are named after the discovery of the photo-transducted channels in Drosophila. TRPs, activated by various extracellular and intracellular stimuli, play a plethora of physiological and pathological roles. There… read more here.
Keywords: classification; trp channel; trp; biology ... See more keywords
TRP Channels in Nociception and Pathological Pain.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-1756-9_2
Abstract: Thermal and noxious stimuli are detected by specialized nerve endings, which transform the stimuli into electrical signals and transmit the signals into central nervous system to facilitate the perception of temperature and pain. Several members… read more here.
Keywords: trp channels; trp; pathological pain; nociception pathological ... See more keywords
Treatment-related pneumonitis after thoracic radiotherapy/chemoradiotherapy combined with anti-PD-1 monoclonal antibodies in advanced esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Strahlentherapie Und Onkologie"
DOI: 10.1007/s00066-024-02199-6
Abstract: This study aims to evaluate the risk factors of treatment-related pneumonitis (TRP) following thoracic radiotherapy/chemoradiotherapy combined with anti-PD‑1 monoclonal antibodies (mAbs) in patients with advanced esophageal squamous cell carcinoma (ESCC). We retrospectively reviewed 97 patients… read more here.
Keywords: grade; radiotherapy; radiotherapy chemoradiotherapy; anti mabs ... See more keywords
Analyzing the genetic characteristics of a tryptophan-overproducing Escherichia coli
Sign Up to like & getrecommendations! Published in 2021 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-021-02552-4
Abstract: L-tryptophan (L-trp) production in Escherichia coli has been developed by employing random mutagenesis and selection for a long time, but this approach produces an unclear genetic background. Here, we generated the L-trp overproducer TPD5 by… read more here.
Keywords: escherichia coli; trp; tryptophan overproducing; genetic characteristics ... See more keywords
A TRiP Through the Roles of Transient Receptor Potential Cation Channels in Type 2 Upper Airway Inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-020-00981-x
Abstract: Despite their high prevalence, the pathophysiology of allergic rhinitis (AR) and chronic rhinosinusitis (CRS) remains unclear. Recently, transient receptor potential (TRP) cation channels emerged as important players in type 2 upper airway inflammatory disorders. In… read more here.
Keywords: trp channels; receptor potential; upper airway; trp ... See more keywords
Effect of Resveratrol, L-Carnitine, and Aromatic Amino Acid Supplements on the Trace Element Content in the Organs of Mice with Dietary-Induced Obesity.
Sign Up to like & getrecommendations! Published in 2021 at "Biological trace element research"
DOI: 10.1007/s12011-021-02642-0
Abstract: Given environmental contamination with toxic metals, diets that promote the elimination of these metals from the body of individuals, including those suffering from obesity, are urgently needed. The aim of this study was to determine… read more here.
Keywords: resveratrol; organs mice; trp; obesity ... See more keywords
Transduction of interaction between trace tryptophan and surface-confined chromium salen using impedance spectroscopy. A sensing device that works based on highly selective inhibition of mediator's Faradaic process.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.05.075
Abstract: It is known that tryptophan (Trp) tends to be electropolymerized over a potential window that is mostly applied for voltammetric determination of Trp. Furthermore, over the applied potential range, most of Trp-sensors suffer from some… read more here.
Keywords: surface confined; confined chromium; sensing device; trp ... See more keywords
Oligomerisation of tryptocidine C, a Trp-rich cyclodecapeptide from the antimicrobial tyrothricin complex.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.12.006
Abstract: Tryptocidine C (TpcC, cyclo[D-Phe1-Pro2-Trp3-D-Trp4-Asn5-Gln6-Trp7-Val8-Orn9-Leu10]) is a broad-spectrum antimicrobial peptide in the tyrothricin complex produced by a soil bacterium, Brevibacillus parabrevis. Electrospray mass spectrometric studies reveal the oligomerisation of TpcC into dimers and higher oligomers, analogous… read more here.
Keywords: tryptocidine; oligomerisation; trp; tpcc ... See more keywords
UV Resonance Raman Characterization of a Substrate Bound to Human Indoleamine 2,3-Dioxygenase 1.
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical journal"
DOI: 10.1016/j.bpj.2019.07.017
Abstract: Human indoleamine 2,3-dioxygenase 1 (IDO) is a heme enzyme that catalyzes the first reaction of the main metabolic pathway of L-tryptophan (Trp) to produce N-formylkynurenin. The reaction involves cleavage of the C2=C3 bond in the… read more here.
Keywords: human indoleamine; trp; reaction; indoleamine dioxygenase ... See more keywords