Kynurenine produced by tryptophan 2,3‐dioxygenase metabolism promotes glioma progression through an aryl hydrocarbon receptor‐dependent signaling pathway
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DOI: 10.1002/cbin.11833
Abstract: The current studies associated with tumor biology continue to describe a high correlation between tryptophan (Trp) metabolism and tumor progression. These findings reflect the complex underlying mechanism of tumor development and highlight the need to… read more here.
Keywords: hydrocarbon receptor; metabolism; trp metabolism; aryl hydrocarbon ... See more keywords
Tryptophan Metabolites as Biomarkers for Esophageal Cancer Susceptibility, Metastasis, and Prognosis
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DOI: 10.3389/fonc.2022.800291
Abstract: Background Perturbation of tryptophan (TRP) metabolism contributes to the immune escape of cancer; however, the explored TRP metabolites are limited, and their efficacy in clarifying the susceptibility and progression of esophageal cancer (EC) remains ambiguous.… read more here.
Keywords: esophageal cancer; trp metabolism; susceptibility; metastasis ... See more keywords
Redox Properties of Tryptophan Metabolism and the Concept of Tryptophan Use in Pregnancy
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DOI: 10.3390/ijms18071595
Abstract: During pregnancy, tryptophan (Trp) is required for several purposes, and Trp metabolism varies over time in the mother and fetus. Increased oxidative stress (OS) with high metabolic, energy and oxygen demands during normal pregnancy or… read more here.
Keywords: trp metabolism; trp metabolites; pregnancy; metabolism ... See more keywords
Pyridoxal 5′-Phosphate-Dependent Enzymes at the Crossroads of Host–Microbe Tryptophan Metabolism
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DOI: 10.3390/ijms21165823
Abstract: The chemical processes taking place in humans intersects the myriad of metabolic pathways occurring in commensal microorganisms that colonize the body to generate a complex biochemical network that regulates multiple aspects of human life. The… read more here.
Keywords: trp metabolism; metabolism; pyridoxal phosphate; host ... See more keywords