Interactive relationship between Trp metabolites and gut microbiota: The impact on human pathology of disease
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DOI: 10.1111/jam.15533
Abstract: Tryptophan (Trp), an α‐amino acid, is the precursor of serotonin (5‐hydroxytryptamine, 5‐HT), which is involved in a variety of features of metabolic function and human nutrition. Evidence highlights the role of Trp metabolites (exclusively 5‐HT)… read more here.
Keywords: relationship trp; gut microbiota; pathology; trp metabolites ... See more keywords
Associations of microbial and indoleamine-2,3-dioxygenase-derived tryptophan metabolites with immune activation in healthy adults
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DOI: 10.3389/fimmu.2022.917966
Abstract: Background Tryptophan (Trp) metabolites from intestinal bacteria (indole, indole acetic acid [IAA] and indole propionic acid [IPA]), and the Trp metabolite kynurenine (Kyn) from the indoleamine 2,3-dioxygenase (IDO) pathway, are aryl hydrocarbon receptor (AhR) agonists… read more here.
Keywords: activation; immune markers; healthy adults; trp metabolites ... See more keywords
Redox Properties of Tryptophan Metabolism and the Concept of Tryptophan Use in Pregnancy
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DOI: 10.3390/ijms18071595
Abstract: During pregnancy, tryptophan (Trp) is required for several purposes, and Trp metabolism varies over time in the mother and fetus. Increased oxidative stress (OS) with high metabolic, energy and oxygen demands during normal pregnancy or… read more here.
Keywords: trp metabolism; trp metabolites; pregnancy; metabolism ... See more keywords