Inactivation of TRP53, PTEN, RB1, and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis
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DOI: 10.1093/biolre/ioaa008
Abstract: Abstract Ovarian cancer (OvCa) remains the most common cause of death from gynecological malignancies. Genetically engineered mouse models have been used to study initiation, origin, progression, and/or mechanisms of OvCa. Based on the clinical features… read more here.
Keywords: cdh1; pten rb1; trp53 pten; inactivation ... See more keywords