SP0022 Trpa1 channels in osteoarthritis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.7275
Abstract: Osteoarthritis (OA) has long been viewed as a degenerative “wear-and-tear” disease of cartilage. There is, however, increasing evidence to confirm that inflammation has a critical role in the pathogenesis and symptoms of the disease. Inflammation… read more here.
Keywords: trpa1; sp0022 trpa1; trpa1 channels; inflammation ... See more keywords
Abstract 14409: TRPA1 Channels Are a Source of Calcium-driven Cellular Mechano-arrhythmogenicity
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.14409
Abstract: Introduction: Pathologic changes in myocardial mechanics and hemodynamic load result in arrhythmias via mechanically-induced changes in electrophysiology or intracellular Ca2+ (‘mechano-arrhythmoge... read more here.
Keywords: mechano; channels source; abstract 14409; source calcium ... See more keywords
TRPA1 channels promote astrocytic Ca2+ hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid-β peptide
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurodegeneration"
DOI: 10.1186/s13024-017-0194-8
Abstract: BackgroundExcessive synaptic loss is thought to be one of the earliest events in Alzheimer’s disease (AD). However, the key mechanisms that maintain plasticity of synapses during adulthood or initiate synapse dysfunction in AD remain unknown.… read more here.
Keywords: hyperactivity; synaptic dysfunction; trpa1 channels; ca2 hyperactivity ... See more keywords