New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca2+ Stores.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-57732-6_13
Abstract: Transient receptor potential canonical (TRPC) proteins were identified as molecular candidates of receptor- and/or store-operated channels because of their close homology to the Drosophila TRP and TRPL. Functional studies have revealed that TRPC channels play… read more here.
Keywords: trpc proteins; trpc; ca2; intracellular ca2 ... See more keywords
Cardiac Remodeling and Disease: SOCE and TRPC Signaling in Cardiac Pathology.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-57732-6_25
Abstract: TRPC channels have been suggested as potential candidates mediating store-operated Ca2+ entry (SOCE) in cardiomyocytes. There is increasing evidence that the TRPC isoforms TRPC1 and TRPC4 might fulfill the function as SOCs, in concert with… read more here.
Keywords: trpc channels; disease; trpc; pathology ... See more keywords
TRPC Channels and Mental Disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1088-4_12
Abstract: Transient receptor potential canonical (TRPC) channels mediate the influx of different types of cations through the cell membrane and are involved in many functions of the organism. Evidences of involvement of TRPC channels in neuronal… read more here.
Keywords: trpc channels; trpc; biology; mental disorders ... See more keywords
Store-operated Ca2+ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63677-2
Abstract: Stromal interaction molecules (STIM1, 2) are acting as sensors for Ca2+ in intracellular stores and activate Orai channels at the plasma membrane for store-operated Ca2+ entry (SOCE), while classical transient receptor potential (TRPC) channel mediate… read more here.
Keywords: trpc; operated ca2; pmlf; receptor ... See more keywords
A Solution to the Non-Ideal Delay Line Problem in Transmitted Reference Pulse Cluster Schemes for UWB Communications
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Internet of Things Journal"
DOI: 10.1109/jiot.2022.3204725
Abstract: The conventional transmitted reference (TR) technique in ultra wide-band (UWB) communications has provided a springboard for a lot of studies, and a TR pulse cluster (TRPC) structure was proved to have robust performance. Most of… read more here.
Keywords: trpc; transmitted reference; design; uwb communications ... See more keywords
Multiprotein Complex With TRPC (Transient Receptor Potential-Canonical) Channel, PDE1C (Phosphodiesterase 1C), and A2R (Adenosine A2 Receptor) Plays a Critical Role in Regulating Cardiomyocyte cAMP and Survival.
Sign Up to like & getrecommendations! Published in 2018 at "Circulation"
DOI: 10.1161/circulationaha.118.034189
Abstract: BACKGROUND cAMP plays a critical role in regulating cardiomyocyte survival. Various cAMP signaling pathways behave distinctly or in opposition. We have previously reported that activation of cAMP hydrolysis by cyclic nucleotide phosphodiesterase 1C (PDE1C) promotes… read more here.
Keywords: death; camp; trpc; receptor ... See more keywords
Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.618663
Abstract: The seven canonical members of transient receptor potential (TRPC) proteins form cation channels that evoke membrane depolarization and intracellular calcium concentration ([Ca2+]i) rise, which are not only important for regulating cell function but their deregulation… read more here.
Keywords: ischemic stroke; trpc channels; contribution; excitotoxicity ... See more keywords
Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2020.00070
Abstract: Stroke remains a leading cause of death, disability, and medical care burden worldwide. However, transformation from laboratory findings toward effective pharmacological interventions for clinical stroke has been unsatisfactory. Novel evidence has been gained on the… read more here.
Keywords: targets stroke; trpc channels; channels trpc6; trpc ... See more keywords
TRPC and TRPV Channels’ Role in Vascular Remodeling and Disease
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DOI: 10.3390/ijms21176125
Abstract: Transient receptor potentials (TRPs) are non-selective cation channels that are widely expressed in vascular beds. They contribute to the Ca2+ influx evoked by a wide spectrum of chemical and physical stimuli, both in endothelial and… read more here.
Keywords: trpc trpv; trpc; vascular remodeling; role ... See more keywords