Stim-activated TRPC-ORAI channels in pulmonary hypertension induced by chronic intermittent hypoxia
Sign Up to like & getrecommendations! Published in 2020 at "Pulmonary Circulation"
DOI: 10.1177/2045894020941484
Abstract: Obstructive sleep apnea (OSA), a breathing disorder featured by chronic intermittent hypoxia (CIH) is associated with pulmonary hypertension (PH). Rodents exposed to CIH develop pulmonary vascular remodeling and PH, but the pathogenic mechanisms are not… read more here.
Keywords: trpc orai; orai; vascular remodeling; cih ... See more keywords
CONTRIBUTION OF STIM-ACTIVATED TRPC-ORAI CHANNELS IN PULMONARY HYPERTENSION INDUCED BY CHRONIC SUSTAINED AND INTERMITTENT HYPOXIA.
Sign Up to like & getrecommendations! Published in 2022 at "Current vascular pharmacology"
DOI: 10.2174/1570161120666220321141805
Abstract: Sustained and intermittent hypoxia produces vasoconstriction, arterial remodeling, and hypertension in the lung. Stromal interaction molecule (STIM)-activated Transient Receptor Potential Channels (TRPC) and Calcium Release-Activated Calcium Channel Protein (ORAI) Channels (STOC) play a key role… read more here.
Keywords: activated trpc; stim activated; intermittent hypoxia; trpc orai ... See more keywords