TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2018.01.003
Abstract: Objective Diabetic retinopathy (DR) is induced by an accumulation of reactive metabolites such as ROS, RNS, and RCS species, which were reported to modulate the activity of cation channels of the TRPC family. In this… read more here.
Keywords: retinopathy; diabetic retinopathy; development diabetic; activity ... See more keywords
Normotensive metabolic syndrome in Transient Receptor Potential Canonical Channel type 1 Trpc1−/− mice.
Sign Up to like & getrecommendations! Published in 2024 at "Biology Open"
DOI: 10.1242/bio.060280
Abstract: ABSTRACT Metabolic syndrome has become a global epidemic, affecting all developed countries and communities with growing economies. Worldwide, increasing efforts have been directed at curbing this growing problem. Mice deleted of the gene encoding Type… read more here.
Keywords: mice; receptor potential; trpc1 mice; transient receptor ... See more keywords