Acetylcholine attenuated TNF-α-induced intracellular Ca2+ overload by inhibiting the formation of the NCX1-TRPC3-IP3R1 complex in human umbilical vein endothelial cells.
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DOI: 10.1016/j.yjmcc.2017.04.001
Abstract: The endoplasmic reticulum (ER) forms discrete junctions with the plasma membrane (PM) that play a critical role in the regulation of Ca2+ signaling during cellular bioenergetics, apoptosis and autophagy. We have previously confirmed that acetylcholine… read more here.
Keywords: ip3r1 complex; ip3r1; endothelial cells; ca2 ... See more keywords