Beta-arrestin-biased agonism promotes TRPC6-mediated calcium influx in human podocytes
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DOI: 10.1152/physiol.2023.38.s1.5731762
Abstract: Background: Angiotensin Receptor blockers (ARBs) are the first-line treatment for hypertension and other chronic kidney diseases and act by inhibiting signaling through the angiotensin 1 receptor (AT1R). AT1R activation initiates signaling through G protein-coupled receptor… read more here.
Keywords: trv; trpc6 mediated; physiology; arrestin ... See more keywords