Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy
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DOI: 10.1371/journal.pone.0231750
Abstract: Melanoma-associated retinopathy (MAR) is a rare paraneoplastic retinal disorder usually occurring in the context of metastatic melanoma. Patients present with night blindness, photopsias and a constriction of the visual field. MAR is an auto-immune disorder… read more here.
Keywords: mar; melanoma associated; associated retinopathy; trpm1 autoantibodies ... See more keywords
A Large Endoplasmic Reticulum-Resident Pool of TRPM1 in Retinal ON-Bipolar Cells
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DOI: 10.1523/eneuro.0143-18.2018
Abstract: Abstract The chemical signal of light onset, a decrease in glutamate release from rod and cone photoreceptors, is processed by a postsynaptic G protein signaling cascade in ON-bipolar cells (BPCs). The metabotropic glutamate receptor mGluR6,… read more here.
Keywords: endoplasmic reticulum; dendritic tips; bipolar cells; trpm1 ... See more keywords