The intracellular Ca2+ channel TRPML3 is a PI3P effector that regulates autophagosome biogenesis
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DOI: 10.1073/pnas.2200085119
Abstract: Significance Autophagy involves multiple fusion events, from autophagosome formation to autophagosome-lysosome fusion in a Ca2+-dependent manner. Fundamental unanswered issue- in the autophagy field is how Ca2+ is provided for autophagic membrane fusion. Here, we report… read more here.
Keywords: pi3p; trpml3; effector; channel ... See more keywords