Articles with "trpv1 modulators" as a keyword



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Structure-Based Virtual Screening Identifies Novobiocin, Montelukast, and Cinnarizine as TRPV1 Modulators with Anticonvulsant Activity In Vivo

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Published in 2022 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.2c00312

Abstract: The transient receptor potential vanilloid 1 (TRPV1) receptor is a nonselective cation channel, known to be involved in the regulation of many important physiological and pathological processes. In the last few years, it has been… read more here.

Keywords: trpv1; trpv1 modulators; virtual screening; novobiocin montelukast ... See more keywords
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Natural Active Ingredients and TRPV1 Modulation: Focus on Key Chemical Moieties Involved in Ligand–Target Interaction

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Published in 2023 at "Plants"

DOI: 10.3390/plants12020339

Abstract: Diseases such as cancer, neurological pathologies and chronic pain represent currently unmet needs. The existing pharmacotherapeutic options available for treating these conditions are limited by lack of efficiency and/or side effects. Transient receptor potential vanilloid… read more here.

Keywords: interaction; ingredients trpv1; trpv1 modulators; natural active ... See more keywords