The omega-3 lipid 17,18-EEQ sensitizes TRPV1 and TRPA1 in sensory neurons through the prostacyclin receptor (IP)
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.107952
Abstract: Oxidized lipids play an important role in pain processing by modulation of the activity of sensory neurons. However, the role of many signalling lipids that do not belong to the classical group of eicosanoids, especially… read more here.
Keywords: trpv1 trpa1; prostacyclin receptor; trpa1 sensory; eeq ... See more keywords
TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch
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DOI: 10.3390/biom11081166
Abstract: Two histamine receptor subtypes (HR), namely H1R and H4R, are involved in the transmission of histamine-induced itch as key components. Although exact downstream signaling mechanisms are still elusive, transient receptor potential (TRP) ion channels play… read more here.
Keywords: induced itch; histamine induced; trpv1 trpa1;