Rational Design and Validation of a Vanilloid-Sensitive TRPV2 Ion Channel
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DOI: 10.1016/j.bpj.2016.11.642
Abstract: Vanilloids activation of TRPV1 represents an excellent model system for ligand gating of ion channels. Recent studies using cryo electron microcopy (cryo-EM), computational analysis and functional quantification revealed the location of capsaicin-binding site and critical… read more here.
Keywords: trpv2; trpv2 quad; rational design; channel ... See more keywords