Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus
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DOI: 10.1016/j.apsb.2021.08.002
Abstract: Abstract Genetic gain-of-function mutations of warm temperature-sensitive transient receptor potential vanilloid 3 (TRPV3) channel cause Olmsted syndrome characterized by severe itching and keratoderma, indicating that pharmacological inhibition of TRPV3 may hold promise for therapy of… read more here.
Keywords: isochlorogenic acid; channel; chronic pruritus; trpv3 channel ... See more keywords