Evidence for TRPV4 channel induced skin vasodilatation through NOS, COX, and KCa channel mechanisms with no effect on sweat rate in humans.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172462
Abstract: Transient receptor potential vanilloid 4 (TRPV4) channels exist in the endothelial cells of cutaneous blood vessels and the secretory cells of eccrine sweat glands. We assessed if exogenous TRPV4 channel activation elicits cutaneous vasodilatation and… read more here.
Keywords: trpv4 channel; vasodilatation; kca channel; sweat rate ... See more keywords
Role of TRPV4 channel in vasodilation and neovascularization
Sign Up to like & getrecommendations! Published in 2021 at "Microcirculation"
DOI: 10.1111/micc.12703
Abstract: The transient receptor potential vanilloid type 4 (TRPV4) channel, a Ca2+‐permeable nonselective cation channel, is widely distributed in the circulatory system, particularly in vascular endothelial cells (ECs) and smooth muscle cells (SMCs). The TRPV4 channel… read more here.
Keywords: trpv4 channel; vasodilation; channel; neovascularization ... See more keywords