Optimized BCMA/CS1 bispecific TRuC-T cells secreting IL-7 and CCL21 robustly control multiple myeloma
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DOI: 10.3389/fimmu.2024.1502936
Abstract: Introduction Challenges remain in reducing antigen escape and tumor recurrence while CAR-T cell therapy has substantially improved outcomes in the treatment of multiple myeloma. T cell receptor fusion construct (TRuC)-T cells, which utilize intact T… read more here.
Keywords: multiple myeloma; tcr cd3; truc; truc cells ... See more keywords