Distinct Mechanisms of β-Arrestin–Biased Agonist and Blocker of AT1R in Preventing Aortic Aneurysm and Associated Mortality
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DOI: 10.1161/hypertensionaha.122.19232
Abstract: Background: Aortic aneurysm (AA) is a “silent killer” human disease with no effective treatment. Although the therapeutic potential of various pharmacological agents have been evaluated, there are no reports of β-arrestin–biased AT1R (angiotensin-II type-1 receptor)… read more here.
Keywords: arrestin biased; trv027; mortality; blocker ... See more keywords