LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "trx" as a keyword



Photo from wikipedia

Exogenous recombinant human thioredoxin‐1 prevents acetaminophen‐induced liver injury by scavenging oxidative stressors, restoring the thioredoxin‐1 system and inhibiting receptor interacting protein‐3 overexpression

Sign Up to like & get
recommendations! Published in 2018 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.3609

Abstract: Thioredoxin‐1 (Trx‐1) is a potent therapeutic agent against a variety of diseases because of its actions as an antioxidant and regulator of apoptosis. N‐acetyl‐p‐aminophenol (APAP), commonly known as acetaminophen, generates excessive oxidative stress and triggers… read more here.

Keywords: overexpression; induced liver; thioredoxin; trx ... See more keywords
Photo from wikipedia

Redox regulation by peroxiredoxins is linked to their thioredoxin-dependent oxidase function

Sign Up to like & get
recommendations! Published in 2019 at "Photosynthesis Research"

DOI: 10.1007/s11120-019-00691-0

Abstract: The chloroplast contains three types of peroxiredoxins (PRXs). Recently, 2-CysPRX was associated with thioredoxin (TRX) oxidation-dependent redox regulation. Here, this analysis was expanded to include PRXQ and PRXIIE. Oxidized PRXQ was able to inactivate NADPH… read more here.

Keywords: oxidase; redox regulation; trx; function ... See more keywords
Photo by ospanali from unsplash

Thioredoxin System Protein Expression Is Associated with Poor Clinical Outcome in Adult and Paediatric Gliomas and Medulloblastomas

Sign Up to like & get
recommendations! Published in 2020 at "Molecular Neurobiology"

DOI: 10.1007/s12035-020-01928-z

Abstract: The thioredoxin (Trx) system is an important enzyme family that regulates cellular redox homeostasis. Protein expression of Trx system family members has been assessed in various cancers and linked to various clinicopathological variables, disease progression,… read more here.

Keywords: protein expression; system; cytoplasmic trxr; trx ... See more keywords
Photo from wikipedia

Thioredoxin and metallothionein: Homeostasis-related proteins in lip carcinogenesis.

Sign Up to like & get
recommendations! Published in 2017 at "Archives of oral biology"

DOI: 10.1016/j.archoralbio.2017.01.020

Abstract: OBJECTIVE Thioredoxin (Trx) and metallothionein (MT) are involved in the development of some carcinomas; however, the role of these proteins in labial carcinogenesis has not yet been tested. The aims of the study were to… read more here.

Keywords: carcinoma; lip mucosa; cheilitis; trx ... See more keywords

Disruption of redox catalytic functions of peroxiredoxin-thioredoxin complex in Mycobacterium tuberculosis H37Rv using small interface binding molecules

Sign Up to like & get
recommendations! Published in 2017 at "Computational biology and chemistry"

DOI: 10.1016/j.compbiolchem.2016.12.013

Abstract: Mycobacterium tuberculosis has distinctive ability to detoxify various microbicidal superoxides and hydroperoxides via a redox catalytic cycle involving thiol reductants of peroxiredoxin (Prx) and thioredoxin (Trx) systems which has conferred on it resistance against oxidative… read more here.

Keywords: interface binding; trx; catalytic functions; redox catalytic ... See more keywords

Perilla aldehyde attenuates CUMS‐induced depressive‐like behaviors via regulating TXNIP/TRX/NLRP3 pathway in rats

Sign Up to like & get
recommendations! Published in 2018 at "Life Sciences"

DOI: 10.1016/j.lfs.2018.05.038

Abstract: Background: Current evidence supports that inflammatory reaction in the hippocampus is a potential cause of major depressive disorder (MDD). Perilla aldehyde (PAH), a major constituent from Perilla frutescens, has been reported to have anti‐inflammatory and… read more here.

Keywords: perilla aldehyde; like behaviors; trx nlrp3; depressive like ... See more keywords
Photo from wikipedia

Binge ethanol and MDMA combination exacerbates HSP27 and Trx‐1 (biomarkers of toxic cardiac effects) expression in right ventricle

Sign Up to like & get
recommendations! Published in 2019 at "Life Sciences"

DOI: 10.1016/j.lfs.2019.01.050

Abstract: Aims: Oxidative stress caused by exposure to drugs of abuse such as ethanol or 3, 4 methylenedioxymethamphetamine (MDMA) may derive from direct or indirect effects in many organs including the heart. The aim of the… read more here.

Keywords: ethanol mdma; mdma; binge ethanol; trx ... See more keywords
Photo by naxph from unsplash

Targeting the Thioredoxin System for Cancer Therapy.

Sign Up to like & get
recommendations! Published in 2017 at "Trends in pharmacological sciences"

DOI: 10.1016/j.tips.2017.06.001

Abstract: Thioredoxin (Trx) and thioredoxin reductase (TrxR) are essential components of the Trx system which plays pivotal roles in regulating multiple cellular redox signaling pathways. In recent years TrxR/Trx have been increasingly recognized as an important… read more here.

Keywords: system; targeting trxr; trxr trx; thioredoxin ... See more keywords
Photo from wikipedia

A 4TX/4RX Pulsed Chirping Phased-Array Radar Transceiver in 65-nm CMOS for X-Band Synthetic Aperture Radar Application

Sign Up to like & get
recommendations! Published in 2020 at "IEEE Journal of Solid-State Circuits"

DOI: 10.1109/jssc.2020.3005809

Abstract: A pulsed chirping phased-array transceiver (TRX) is demonstrated for X-band synthetic aperture radar (SAR) application. The phased-array TRX is implemented on a single CMOS chip with beamsteering/beamforming capabilities. The chip-scale radar TRX is composed of… read more here.

Keywords: trx; array radar; phased array; pulsed chirping ... See more keywords
Photo by ohkimmyphoto from unsplash

Highly Integrated In-Band Full-Duplex TRx Antennas for mmWave V2X Communications

Sign Up to like & get
recommendations! Published in 2023 at "IEEE Transactions on Vehicular Technology"

DOI: 10.1109/tvt.2023.3236311

Abstract: A compact mmWave co-circularly polarized (CP) Tx and Rx (TRx) antenna array for in-band full-duplex (IBFDX) V2X communications is proposed. The proposed TRx antenna is based on highly integrated coplanar TRx antenna elements with high… read more here.

Keywords: band; full duplex; trx antenna; v2x communications ... See more keywords

Thioredoxin‐1 regulates the autophagy induced by oxidative stress through LC3‐II in human lens epithelial cells

Sign Up to like & get
recommendations! Published in 2023 at "Clinical and Experimental Pharmacology and Physiology"

DOI: 10.1111/1440-1681.13764

Abstract: Oxidative stress plays a major role in age‐related cataract development. The cellular antioxidant protein thioredoxin‐1 (Trx‐1) and its negative regulator, thioredoxin binding protein‐2 (TBP‐2), are pivotal in the cellular redox balance during oxidative stress. The… read more here.

Keywords: trx tbp; oxidative stress; tbp; trx ... See more keywords