Abstract 3710: Serum tryptophan metabolites mediate constitutive AHR activity in head and neck squamous cell carcinoma cells
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DOI: 10.1158/1538-7445.am2023-3710
Abstract: The aryl hydrocarbon receptor (AHR) is transcription factor, that is activated upon binding to various exogenous and endogenous ligands. AHR activation leads to induction of target gene expression, including the members of cytochrome P450 enzyme… read more here.
Keywords: tryp; tryp metabolites; cell; ahr activation ... See more keywords
Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis
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DOI: 10.3389/fphar.2020.01145
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease involving joint and bone damage that is mediated in part by proteases and cytokines produced by synovial macrophages and fibroblast-like synoviocytes (FLS). Although current biological therapeutic strategies… read more here.
Keywords: tryptanthrin oxime; rheumatoid arthritis; tryp; tryp tryp ... See more keywords