Heterobimetallic nickel(II) and palladium(II) complexes derived from S-benzyl-N- (ferrocenyl)methylenedithiocarbazate: Trypanocidal activity and interaction with Trypanosoma cruzi Old Yellow Enzyme (TcOYE).
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.07.014
Abstract: Reactions of Ni(II) and Pd(II) precursors with S-benzyl-N-(ferrocenyl)methylenedithiocarbazate (HFedtc) led to the formation of heterobimetallic complexes of the type [MII(Fedtc)2] (M = Ni and Pd). The characterization of the compounds involved the determination of melting point, FTIR,… read more here.
Keywords: cruzi; benzyl ferrocenyl; ferrocenyl methylenedithiocarbazate; trypanocidal activity ... See more keywords
Ex vivo trypanocidal activity of 1-(2-hydroxybenzylidene)thiosemicarbazide against Trypanosoma equiperdum.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2017.06.012
Abstract: Trypanosoma equiperdum is the causative agent of dourine, a venereal disease in horses and donkeys. This parasite has a widely distribution, is found in Africa, Asia, Southern and Eastern Europe, Russia, Mexico and Venezuela. The… read more here.
Keywords: trypanosoma equiperdum; trypanocidal activity; activity; equiperdum vivo ... See more keywords
Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01330-20
Abstract: A common strategy to identify new antiparasitic agents is the targeting of proteases, due to their essential contributions to parasite growth and development. Metacaspases (MCAs) are cysteine proteases present in fungi, protozoa, and plants. ABSTRACT… read more here.
Keywords: identification metacaspase; trypanocidal activity; activity; mechanism ... See more keywords
Trypanocidal Activity of Four Sesquiterpene Lactones Isolated from Asteraceae Species
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DOI: 10.3390/molecules25092014
Abstract: The sesquiterpene lactones eupatoriopicrin, estafietin, eupahakonenin B and minimolide have been isolated from Argentinean Astearaceae species and have been found to be active against Trypanosoma cruzi epimastigotes. The aim of this work was to evaluate… read more here.
Keywords: sesquiterpene; sesquiterpene lactones; four sesquiterpene; activity four ... See more keywords