Articles with "trypanosoma" as a keyword



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Identification of Phenylpyrazolone Dimers as a New Class of Anti‐Trypanosoma cruzi Agents

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Published in 2019 at "Chemmedchem"

DOI: 10.1002/cmdc.201900370

Abstract: Chagas disease is becoming a worldwide problem; it is currently estimated that over six million people are infected. The two drugs in current use, benznidazole and nifurtimox, require long treatment regimens, show limited efficacy in… read more here.

Keywords: new class; dimers new; phenylpyrazolone dimers; identification phenylpyrazolone ... See more keywords
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Rodent-borne Trypanosoma from cities and villages of Niger and Nigeria: A special role for the invasive genus Rattus?

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Published in 2017 at "Acta tropica"

DOI: 10.1016/j.actatropica.2017.03.027

Abstract: Although they are known to sometimes infect humans, atypical trypanosomes are very poorly documented, especially in Africa where one lethal case has yet been described. Here we conducted a survey of rodent-borne Trypanosoma in 19… read more here.

Keywords: villages niger; niger nigeria; rodent borne; borne trypanosoma ... See more keywords
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Andrographolide induces oxidative stress-dependent cell death in unicellular protozoan parasite Trypanosoma brucei.

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Published in 2017 at "Acta tropica"

DOI: 10.1016/j.actatropica.2017.07.023

Abstract: African sleeping sickness is a parasitic disease in humans and livestock caused by Trypanosoma brucei throughout sub-Saharan Africa. Absence of appropriate vaccines and prevalence of drug resistance proclaim that a new way of therapeutic interventions… read more here.

Keywords: andro; trypanosoma brucei; trypanosoma; cell ... See more keywords
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The kinetoplast DNA of the Australian trypanosome, Trypanosoma copemani, shares features with Trypanosoma cruzi and Trypanosoma lewisi.

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Published in 2018 at "International journal for parasitology"

DOI: 10.1016/j.ijpara.2018.02.006

Abstract: Kinetoplast DNA (kDNA) is the mitochondrial genome of trypanosomatids. It consists of a few dozen maxicircles and several thousand minicircles, all catenated topologically to form a two-dimensional DNA network. Minicircles are heterogeneous in size and… read more here.

Keywords: kinetoplast dna; trypanosoma copemani; lewisi; trypanosoma ... See more keywords
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Uncovering Trypanosoma spp. diversity of wild mammals by the use of DNA from blood clots

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Published in 2019 at "International Journal for Parasitology: Parasites and Wildlife"

DOI: 10.1016/j.ijppaw.2019.02.004

Abstract: Trypanosoma spp. infection in wild mammals is detected mainly through parasitological tests that usually display low sensitivity. We propose the use of DNA extracted directly from blood clots (BC), which are neglected sources of DNA… read more here.

Keywords: blood clots; wild mammals; use dna; diversity ... See more keywords
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Involvement of STI1 protein in the differentiation process of Trypanosoma cruzi.

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Published in 2018 at "Parasitology international"

DOI: 10.1016/j.parint.2017.10.009

Abstract: The protozoan Trypanosoma cruzi is a parasite exposed to several environmental stressors inside its invertebrate and vertebrate hosts. Although stress conditions are involved in its differentiation processes, little information is available about the stress response… read more here.

Keywords: protein; differentiation process; differentiation; cruzi ... See more keywords
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Epidemiology of Babesia, Anaplasma and Trypanosoma species using a new expanded reverse line blot hybridization assay.

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Published in 2018 at "Ticks and tick-borne diseases"

DOI: 10.1016/j.ttbdis.2017.08.011

Abstract: Vector-borne hemoparasitic infections are a major problem that affects livestock industries worldwide, particularly in tropical and subtropical regions. In this work, a reverse line blot (RLB) hybridization assay was developed for the simultaneous detection and… read more here.

Keywords: hybridization assay; epidemiology; anaplasma; reverse line ... See more keywords
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A Trypanosoma species detected in Rhipicephalus (Boophilus) microplus ticks from Argentina.

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Published in 2020 at "Ticks and tick-borne diseases"

DOI: 10.1016/j.ttbdis.2020.101573

Abstract: Specimens of a Trypanosoma sp. were found in a haemolymph sample of Rhipicephalus microplus from Argentina. Polymerase chain reaction (PCR) was done targeting the SSU rRNA gene of Trypanosoma spp. and a fragment of 2300… read more here.

Keywords: detected rhipicephalus; trypanosoma species; species detected; rhipicephalus boophilus ... See more keywords
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Identification of potential protein partners that bind to the variant surface glycoprotein in Trypanosoma equiperdum

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Published in 2017 at "Parasitology"

DOI: 10.1017/s003118201700004x

Abstract: SUMMARY Trypanosoma equiperdum possesses a dense coat of a variant surface glycoprotein (VSG) that is used to evade the host immune response by a process known as antigenic variation. Soluble and membrane forms of the… read more here.

Keywords: protein; vsg; trypanosoma equiperdum; surface ... See more keywords
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Infection with Trypanosoma lewisi or Trypanosoma musculi may promote the spread of Toxoplasma gondii

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Published in 2021 at "Parasitology"

DOI: 10.1017/s0031182021000196

Abstract: Abstract Abstract Toxoplasma gondii can infect almost all warm-blooded vertebrates with pathogensis being largely influenced by the host immune status. As important epidemiological hosts, rodents are globally distributed and are also commonly found infected with… read more here.

Keywords: toxoplasma gondii; infection; trypanosoma; musculi ... See more keywords
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Molecular detection of Trypanosoma (Trypanosomatidae) in bats from Thailand, with their phylogenetic relationships

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Published in 2022 at "Parasitology"

DOI: 10.1017/s0031182022000117

Abstract: Abstract Abstract The vast majority of trypanosome species is vector-borne parasites, with some of them being medically and veterinary important (such as Trypanosoma cruzi and Trypanosoma brucei) and capable of causing serious illness in vertebrate… read more here.

Keywords: bat; thailand phylogenetic; bats thailand; phylogenetic relationships ... See more keywords