Anti-trypanosomal activity of doubly modified salinomycin derivatives.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.03.061
Abstract: As a group of biologically active compounds, polyether antibiotics (ionophores) show a broad spectrum of interesting pharmacological properties, ranging from anti-bacterial to anti-cancer activities. There is increasing evidence that ionophores, including salinomycin (SAL), and their… read more here.
Keywords: trypanosomal activity; sal; doubly modified; anti trypanosomal ... See more keywords
Naphthoquinone derivatives exhibit apoptosis-like effect and anti-trypanosomal activity against Trypanosoma evansi.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2021.109367
Abstract: Trypanosoma evansi is an extracellular flagellate blood protozoan parasite and an etiological agent of animal trypanosomosis. Presently, only a few drugs are registered and have been used for the treatment of animal trypanosomosis, but they… read more here.
Keywords: trypanosomal activity; activity; effect; anti trypanosomal ... See more keywords