A New N-Fatty Acyl Tryptamine from Annana atemoya
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-020-03235-4
Abstract: A new N-fatty acyl tryptamine, N-nonadecanoyl-4,5-dihydroxytryptamine (1), was isolated from the stems of Annona atemoya. The structure of the new tryptamine-derived amide was elucidated by chemical and physical evidence. read more here.
Keywords: fatty acyl; annana atemoya; acyl tryptamine; new fatty ... See more keywords
N-Pyrenylmethoxycarbonyl phototriggers for the release of serotonin, tryptamine and their biosynthetic precursors
Sign Up to like & getrecommendations! Published in 2018 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2018.01.021
Abstract: Abstract An evaluation of the pyrenylmethoxycarbonyl group as a photolabile protecting group for the amino function, using neuroactive amines and amino acids as models, was carried out. 1-Hydroxymethylpyrene was reacted with serotonin and tryptamine and… read more here.
Keywords: tryptamine biosynthetic; release serotonin; phototriggers release; pyrenylmethoxycarbonyl phototriggers ... See more keywords
Vasodilator Effect of Trace Amines, 3-Iodothyronamine, and RO5263397 in the Rat Perfused Kidney: Comparison with Tryptamine.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacology"
DOI: 10.1159/000530649
Abstract: INTRODUCTION Trace amine-associated receptors (TAARs) are a family of G protein-coupled receptors and are widely distributed in the body. Activation of TAAR1 by specific agonists can produce a variety of physiological effects centrally and peripherally.… read more here.
Keywords: tryptamine; vasodilator; vasodilator responses; t1am ro5263397 ... See more keywords
Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
Sign Up to like & getrecommendations! Published in 2017 at "Microbiome"
DOI: 10.1186/s40168-017-0297-z
Abstract: BackgroundThe gut microbiota of breast-fed and formula-fed infants differ significantly, as do the risks for allergies, gut dysfunction, and upper respiratory tract infections. The connections between breast milk, various formulas, and the profiles of gut… read more here.
Keywords: microbiota; formula; colon; tryptophan metabolism ... See more keywords
Unraveling human transferrin-tryptamine interactions: a computational and biophysical approach to Alzheimer’s disease therapeutics
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2025.1540736
Abstract: Neurodegeneration is a progressive loss of neurons that leads to affected cognitive and motor functions and is characterized by neurodegenerative disorders (NDs). Human transferrin (Htf) is a blood plasma glycoprotein that binds to iron and… read more here.
Keywords: alzheimer disease; tryptamine; iron; human transferrin ... See more keywords
Dual Effect of Tryptamine on Prostate Cancer Cell Growth Regulation: A Pilot Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911087
Abstract: Abnormal tryptophan metabolism is linked to cancer and neurodegenerative diseases, and tryptophan metabolites have been reported as potential prostate cancer (PCa) biomarkers. However, little is known about the bioactivities of tryptophan metabolites on PCa cell… read more here.
Keywords: tryptamine; cell; growth; prostate ... See more keywords
The First Noncovalent-Bonded Supramolecular Frameworks of (Benzylthio)Acetic Acid with Proline Compounds, Isonicotinamide and Tryptamine
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DOI: 10.3390/molecules27238203
Abstract: The co-crystallization of (benzylthio)acetic acid (HBTA) with L-proline (L-PRO), D-proline (D-PRO), DL-proline (DL-PRO), isonicotinamide (INA) and tryptamine (TPA) led to the formation of five novel crystalline compounds: L-PRO±·HBTA (1), D-PRO±·HBTA (2), DL-PRO±·HBTA (3), INA·HBTA (4)… read more here.
Keywords: benzylthio acetic; tryptamine; acetic acid; proline pro ... See more keywords
Potential of Tryptamine Derivatives as Multi-Target Directed Ligands for Alzheimer’s Disease: AChE, MAO-B, and COX-2 as Molecular Targets
Sign Up to like & getrecommendations! Published in 2024 at "Molecules"
DOI: 10.3390/molecules29020490
Abstract: Extensive research has been dedicated to develop compounds that can target multiple aspects of Alzheimer’s disease (AD) treatment due to a growing understanding of AD’s complex multifaceted nature and various interconnected pathological pathways. In the… read more here.
Keywords: alzheimer disease; target directed; tryptamine; directed ligands ... See more keywords