Synthesis and Anticancer Evaluation of Tryptanthrin‐1,2,3‐Triazole Hybrids
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DOI: 10.1002/jhet.4916
Abstract: Synthesis of 18 tryptanthrin‐triazole hybrid molecules by employing Cu(I)‐catalyzed azide‐alkyne [3 + 2] cycloaddition (CuAAC) between tryptanthrin oxime O‐propargyl ether and aromatic azides is described here. The exclusive formation of E‐triazoles was confirmed by theoretical studies using… read more here.
Keywords: synthesis anticancer; tryptanthrin triazole; anticancer evaluation; tryptanthrin ... See more keywords
Tryptanthrin Reduces Campylobacter jejuni Colonization in the Chicken Gut by a Bactericidal Mechanism
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DOI: 10.1128/aem.01701-22
Abstract: Campylobacter is a widespread pathogen in the food chain of chickens. Once chickens become infected, large numbers of Campylobacter cells are excreted in their feces. ABSTRACT Campylobacter jejuni is a leading cause of foodborne bacterial… read more here.
Keywords: chicken; campylobacter; bactericidal; tryptanthrin ... See more keywords
The Natural Alkaloid Tryptanthrin Induces Apoptosis-like Death in Leishmania spp.
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DOI: 10.3390/tropicalmed7060112
Abstract: Leishmaniasis is a vector-borne disease against which there are no approved vaccines, and the treatment is based on highly toxic drugs. The alkaloids consist of a chemical class of natural nitrogen-containing substances with a long… read more here.
Keywords: natural alkaloid; like death; leishmania; tryptanthrin ... See more keywords